Product Name:Risperidone
CAS #:106266-06-2
Mode of Action:
Blockade of dopaminergic D_ receptors in the limbic system alleviates positive symptoms of schizophrenia such as hallucinations, delusions, and erratic behavior and speech. Blockade of serotonergic 5-HT_ receptors in the mesocortical tract, causes an excess of dopamine and an increase in dopamine transmission, resulting in an increase in dopamine transmission and an elimination of core negative symptoms. Dopamine receptors in the nigrostriatal pathway are not affected by risperidone and extrapyramidal effects are avoided. Like other 5-HT_ antagonists, risperidone also binds at alpha(1)-adrenergic receptors and, to a lesser extent, at histamine H1 and alpha(_)-adrenergic receptors.
IUPAC:
3-{2-[4-(6-fluoro-1, 2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4H, 6H, 7H, 8H, 9H-pyrido[1, 2-a]pyrimidin-4-one
Formula: C16 – H21 – N5 – O2
Molecular Mass: 410.484