Product Name: Loxoprofen
CAS #: 68767-14-6
Mode of Action:
Loxoprofen itself is a prodrug and carries little-to-no pharmacological activity – it is rapidly metabolized to its trans-alcohol form, which is a potent and non-selective inhibitor of cyclooxygenase. Cyclooxygenase (COX) is present in 2 forms, COX-1 and COX-2, with each serving different functions. COX-1 is present in human cells and is constitutively released, performing cellular housekeeping functions such as mucus production and platelet aggregation. COX-2 is induced in human cells post-injury or due to other stimuli, is triggered to appear in large quantities at the sites of injury/stimuli, and is ultimately responsible for the mediation of inflammation and pain
IUPAC:
2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoic acid
Formula: C15-H18-O3
Molecular Mass: 246.3g/mol